As a consequence, omics platforms and individual omics profiles are expected to become fairly affordable and data generation is no more a bottleneck for most laboratories, at least in the middle and high-income countries [ 34].
As high-throughput techniques increase the availability of completely sequenced organisms, annotation of protein function becomes more and more a bottleneck in the progress of biomolecular sciences and the gap between available sequence data and functionally characterized proteins is still widening [ 2].
As time progressed, the bypass became more and more of a bottleneck as roads around it were improved to higher standards, particularly after the opening of the A33 Chandler's Ford Bypass in 1968 and the A34 King's Worthy Link the following year, which meant all long distance traffic, as opposed to merely that from London to Southampton, was using the bypass.
As the organization grows, the more decisions you choose to be involved in, the more of a bottleneck you will become.
His departure could make Spiegel even more of a bottleneck for design decisions at a time when Snapchat's trying to evolve amidst stern competition from fast-moving Facebook subsidiary Instagram.
The median size of angel deals rose to $640,000 in the third quarter of last year — a five-quarter high — as startups looked for more runway amid a bottleneck for Series A rounds.
The administration has also registered asylum seekers more slowly, creating a bottleneck at the border, said Kevin Malone, executive director of the San Diego Organizing Project, a member of the coalition.
Low MC values are more conservative as a bottleneck must be of greater intensity to drop below this level [ 82]; for this reason, the lowest obtained MC value was used to check bottleneck significance.
With the continuous growing demand for high voltage level and power transmission capacity, these defects are represented more and more obviously, which become a bottleneck for application of the two-level or three-level technology.
Later, these branches will evolve and become more isolated, resulting in a 'Bottleneck Effect' that can result in chromosomal instability, allowing further expansion of tumor heterogeneity [ 26].
For Hawaii (K2), the posterior distribution displays values lower than 1 and shows a peak at 0.59 indicating a more severe bottleneck than in Australia (Fig. 4E).
