Exact(6)
Although primarily not designed to prediet outcome any assessment of morbidity must be related to mortality to some degree.
Morbidity must be kept to negligible levels, especially for patients with ductal carcinoma in situ (DCIS) and good prognosis tumours with cure rates of 80% 95%.
Several categories that reflect medical practices rather than true morbidity must be viewed with caution, even when they have good predictive performance (overuse of medication).
However the benefits of alleviating morbidity must be balanced against potential toxicity of chronic imatinib therapy in this relatively young patient population.
Increasing the number of women birthing with skilled birth attendants (SBAs) as one of the strategies to reduce maternal mortality and morbidity must be partnered with a minimum standard of care.
Following similar progress in other areas of medicine [ 45], ML approaches for forecasting post-traumatic morbidity must be extended and enriched using other data sets and adding other putative predictors.
Similar(54)
If there is a wide centre variation in practices or morbidities, standardising current practices or preventing morbidities must be considered first.
Other particulars of these patients such as associated illnesses and co-morbidities must be kept in mind before taking a final decision.
According to the theory that the associations among morbidities must be involved when comorbidity rates exceed those that are statistically expected (coincidental) [ 34], hierarchical cluster analysis helps identify the conjunction between morbidities in a small population with a high prevalence of multimorbidity.
In order to meet this explicit patient wish, it is indispensable that PFS as a morbidity parameter must be viewed as imminently useful and valuable to the affected patient.
In summary, for proving an additional PRB in oncology, morbidity endpoints must be considered in addition to mortality and HRQoL in order to adequately address the complexity of the situation of the individual patient and his or her treating physicians (see Figure 2).
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