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Furthermore, the loss of productivity associated with hospitalisation and morbidity has a detrimental impact on the economy.
These findings imply that treatment morbidity has a negative effect on QoL scale scores for many years after treatment.
Preterm birth (PTB), a leading cause of infant mortality and morbidity, has a complex etiology with a multitude of interacting causes and risk factors.
Additionally, the ideal CSBD animal model creates little to no animal morbidity, has a low risk of complications, can provide more than one defect per animal in order to reduce the number of animals, can be imaged easily with advanced imaging techniques, and is reproducible.
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Gomez et al. [34] showed that fetuses with severe neonatal morbidity had a lower mean GA and a higher proportion of CA. Furthermore, these fetuses had significantly higher levels of IL-6 in amniotic fluid and fetal plasma [34].
The presence of a cardiovascular morbidity had a sensitivity of 65.7% and a specificity of 48.6%.
Moreover, some studies have shown that postoperative morbidity had a negative impact on long-term outcomes following radical surgery of various tumors [ 46- 48].
However, although the combined end point of mortality and morbidity had a slightly lower incidence in the picotamide group, this difference did not reach statistical significance.
In a study from Finland, younger patients suffering from moderate depression and with co- morbidity had a lower responder rate as compared to severely depressed older patients without co-morbidity [ 13].
Compared with moderate or lower morbidity, individuals with high morbidity had a 30% higher rate of ongoing use (rate ratio 1.30, 95% CI 1.16 1.45, P < 0.001), and individuals with very high morbidity had 21% higher use (rate ratio 1.21, 95% CI 1.07 1.37, P = 0.003).
The presence of co-morbidity has a pervasive effect on QoL, research, and clinical practice through its influence on diagnosis, prognosis, treatment and, health care delivery.
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