Information on morbidity, availability of healthcare, utilization of healthcare and healthcare expenditures of the sampled population are summarized in Table 2. a SE = Standard Error.
Autologous bone grafts are the gold standard, but their clinical use is limited by donor site morbidity, availability, additional surgery, bone resorption at the recipient site, and difficulties with three-dimensional contouring [ 3, 4].
Invasive meningococcal disease (IMD) is associated with significant case fatality and long-term morbidity despite availability of effective antibiotics and intensive care support in industrialised countries [ 1, 2].
However, each of these has disadvantages such as donor site morbidity, limited availability, and two-stage surgery (van Bergen et al. 2008, Paul et al. 2009).
The final topic is chosen by an Independent Advisory Group on the basis of its importance in terms of the burden of morbidity, the availability of national standards against which to assess care and so the potential for an impact on improved care and improved patient outcome, and the practicality of identifying cases.
Several parameters other than efficacy and safety (such as co-morbidity, costs, availability of other therapies, patient and physician expectations, and medication compliance) have an impact on the rate of discontinuation of a drug [ 48].
The probability of being in treatment can depend on several factors not related to the burden of morbidity, such as availability of services, their location and accessibility and the rate of their utilisation.
The standard of care, vascularized bone grafts, is limited by donor site morbidity and restricted availability.
Ideal tendon repair materials combine minimal donor-site morbidity and ready availability with excellent healing and postoperative function.
However, donor site morbidity, limited bone availability, unpredictable resorption rates, and residual deformities remain important challenges [4].
All animals in this study were observed at least once daily for signs of mortality, morbidity, injury, and availability of food and water.
