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Table 3 Technique morbidity analysis Ma and Griffith Tenolig P value Media (DS) Num.
Survival and morbidity analysis will be carried out by performing χ and log-rank tests.
JMI built the demographic-clinical database and performed the morbidity analysis.
* Morbidity analysis was performed for 38 patients, since Glasgow outcome scale was not available for five patients.
The cohort considered in the present study comprised 5,627 workers for the mortality analysis and 5,431 for the morbidity analysis.
The restriction criteria adopted for the morbidity analysis implied the exclusion of subjects deceased before 2003, possibly resulting in a survival cohort selected because of good health status.
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Cons: No behavioural assays, no co-morbidity analysis, no system-wide or whole-organism screening.
Challenges addressed: Genetic interactions and variant analysis, whole-animal phenotypes for biomarkers and co-morbidity analysis, large-scale therapeutic development.
Cons: Immature or partial organs only; no ability for co-morbidity analysis, no systems/whole-organism toxicity screen.
Zebrafish: Challenges addressed: genetic interactions and variant analysis, whole-animal phenotypes for biomarkers and co-morbidity analysis, mid- to large-scale therapeutic development.
Box 2. Whole-animal approaches Invertebrates: Challenges addressed: Genetic interactions and variant analysis, whole-animal phenotypes for biomarkers and co-morbidity analysis, large-scale therapeutic development.
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