This is Tasmanian festival Dark Mofo's one-off Funeral Party: a gothic ball dripping in dark excess, with morbid, immersive performance art in every nook and coffin.
We included, however, the score for pre-morbid functional performance, which reflects also aspects of neurological problems, such as dementia.
Unmatched AKI patients had worse pre-morbid functional performance and more comorbidities than matched AKI patients (Additional file 1: Table S2).
Accordingly, instead of AKI, we found COPD, chronic liver failure, CKD, rheumatoid diseases, poor pre-morbid functional performance, and advanced age to associate with worse long-term outcome.
However, after adjustments using Cox proportional hazards regression, AKI was not associated with decreased 3-year survival (HR 1.05; CI 95% 0.86 1.27), whereas advanced age, poor pre-morbid functional performance, and presence of several comorbidities were.
Women also show lower pre-morbid cognitive performance [ 23] and the course of the illness is considerably less severe [ 24].
However, it is appreciated in this study that age is associated with other co-morbid conditions, and performance status, which may contraindicate chemotherapy and it remains to be determined if the apparent age effect is independent of these factors.
Interestingly, when psychological factors were included in the analysis, variables previously found to be significantly associated with functional limitation, including current tobacco use, education level, gender, and number of co-morbid medical conditions, performance of back exercises failed to show significance.
There was a trend for higher pre-morbid IQ to improve performance on cognitive scores over time for most tests relative to lower pre-morbid IQ, with higher pre-morbid IQ being particularly associated with relative improvement in lexical verbal fluency, though this may reflect a relative lack of novelty on repeated testing.
Presence of co-morbid RA predicted lower performance of A1c testing among older adults with diabetes.
