Sentence examples similar to morbid inflammation from inspiring English sources

Moreover, given the clear contribution of co-morbid inflammation to disease progression, it is important that patients with such co-morbidities are not excluded from clinical trials of novel or repurposed drugs for AD.

This is a feature of osteoarthritis co-morbid with inflammation or the metabolic syndrome.

Generalized, polyarticular osteoarthritis and local, monoarticular osteoarthritis appear to be two different profiles; the former is a feature of osteoarthritis co-morbid with inflammation or the metabolic syndrome, while the latter is more typical of post-trauma osteoarthritis, especially in cases with severe malalignment.

A morbid, preening excitement.

CKD is an independent risk factor for the development of gout [ 10, 11] yet there are several reasons to explain why gout may predispose to renal disease, including hyperuricaemia, chronic inflammation, co-morbid hypertension and diabetes mellitus, and use of nonsteroidal anti-inflammatory drugs.

In addition to its role in hematopoietic differentiation, osteoclastogenesis, and embryonic stem cells differentiation, as well as in carcinogenesis, miR-223 also has an instrumental role in inflammatory diseases, such as adipocyte inflammation associated with morbid obesity, insulin resistance, rheumatoid arthritis, vascular damage, and atherosclerosis [ 3, 32, 49– 52].

Clinical studies of pathophysiological changes during sepsis are potentially confounded by the absence of a well-defined onset time of inflammation, by significant co-morbid conditions, as well as by considerable delays from the presumed initiation of inflammation until study inclusion.

ApoE knockout (ApoE−/−) mice provided a high fat western diet develop morbid obesity and have evidence of chronic inflammation.

In a subset of depressed patients, the balance between pro- and anti-inflammatory cytokines is thought to be altered, causing mood symptoms due to inflammation, as seen in co-morbid depression associated with inflammatory conditions (e.g. psoriasis, hepatitis C, inflammatory bowel disease, rheumatoid arthritis, ankylosing spondylitis).

Protein-energy malnutrition is a major risk factor for mortality and inflammation; the presence of co-morbid conditions like cardiovascular disease increases this risk further [ 3- 7].

Our results further lend support to this concept, as we could demonstrate that lean patients are generally more fluid overloaded while it is known that fluid overloaded individuals comprise the more morbid patient group with higher markers of the malnutrition-inflammation complex syndrome (MICS) [ 18, 39].