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However, the mooring sequence was not conserved between mouse and human beta-2 microglobulin transcripts.
For each of the 5 transcripts, the positions of the 17 base NlaIII tag and the mooring sequence were determined.
Moreover, the RNA-editing site occurs in a 16 base region directly 5' to the mooring sequence.
None of the 17 base NlaIII tags could be potentially edited by APOBEC1 because the mooring sequence and the tag were distant from each other in the transcript sequence (Additional file 8).
Using an APOBEC1 specific editing sequence pattern, namely WCWN2-4WRAUYANUAU (mooring sequence), which is located directly 3' to the edited cytosine, Rosenberg B. R. et al. predicted 376 editing sites in 363 distinct mouse transcripts.
Finally, proximity between the 17 base NlaIII tag and the mooring sequence was determined and the possibility that the 17 base NlaIII tag could be edited by the APOBEC1 enzyme was assessed.
Similar(54)
These transcripts were compared with the mouse orthologues to determine the local level of similarity between mouse and human mooring sequences.
When the mooring sequences were conserved between mouse and human, the 17 base NlaIII tag was localized on the human transcript.
This paper presents a new procedure for the optimization of the mooring design of floating platforms, in which an automatic design sequence is also established.
Comparing the transcript sequences surrounding the C to U edition position, a mooring pattern, i.e. WCWN2-4WRAUYANUAU, had been defined.
Three miles of mooring chains.
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