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Patients with stable central nervous system (CNS) metastasis (for at least 3 months) were permitted.
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Reduction of MTX dosage in the first 6 months was permitted only in cases of toxicity.
5FU treatment was planned to be administered for 6 months, however, prolonged 5FU administration beyond 6 months was permitted.
Prolonged therapy beyond 12 months was permitted whether it was determined that a patient would derive benefit from continued therapy.
For example, when CD4 counts were observed monthly, the same participants were identified for treatment initiation, regardless of whether a grace period of 1 or 12 months was permitted.
The primary outcome was self reported, prolonged abstinence from the quit date to six months; lapses were permitted provided no more than five cigarettes in total were smoked.
Most of the victims were from the P.P.P. Once a month, the women were permitted visitors, but only family members.
In the first month after public demonstrations were permitted at Speakers' Corner, 11 out of the 31 applications received were indicated as being public protests.
Intervention group participants who wore flat insoles (or had been wearing contoured foot orthoses for more than 3 months) in their current footwear were permitted to wear them in their study footwear, provided that the fit of the shoes was appropriate.
Contact sports were permitted after 7 months postoperatively.
In the months that followed (296 days), residents were permitted to return to their homes in the exclusion zone between 09.00 and 14 00 (known as daytime entry), although access was withheld during periods of raised activity, due to the heightened risk of pyroclastic flows traveling down the valley.
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