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If there is stable disease after 6 months of induction chemotherapy but unacceptable toxicities, radiation therapy may be offered as an alternative.
We also analyzed the cells for markers for photoreceptor differentiation at the end of 2 months of induction.
Although EGFP positive cells were eventually detected in the blood of all triple transgenic mice, in the best case less than 10 percent of peripheral blood leukocytes were labeled following nine months of induction (Figure 2E).
The histopathological analysis of liver sections from Rb and MYC/Rb mice after 5 months of induction of the MYC transgene and deletion of Rb showed accumulation of hepatocytes with large nuclei compared to control mice, before the appearance of tumors (Figure 5C).
Outcomes are particularly poor following immunochemotherapy failure or relapse within 12 months of induction.
The standard treatment for proliferative LN involves three to six months of induction therapy with either MMF or cyclophosphamide.
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The antebrachiocarpal joint after 2 months of OA induction and 6 month of no treatment showed severe articular surface degeneration affecting the carpal bones.
After 12 months of treatment, induction of anti-dsDNA autoantibodies was observed in 10 of 23 (46.5%) infliximab-treated RA patients, 3 of 13 (23%) AS patients and 2 of 30 (6.7%) control patients.
After 12 months of therapy, induction of ANA was observed in 16 of 57 (28%) adalimumab-treated patients with RA, and in 8 of 55 (14.5%) with methotrexate only (Table 5).
Patients who had disease recurrence (Ta G3, T1 G1-3 TCC) within 6 months of one induction cycle and at least three maintenance cycles of BCG, with no residual disease after TURB, were consecutively enrolled onto this phase II study.
Maintenance treatment is considered by six studies including comparisons of AZA after 3 months of remission induction with continued CPA[ 39], AZA and MMF[ 40], AZA and Methotrexate[ 23], Methotrexate and Leflunomide[ 22], the use of co-trimoxazole[ 41] and etanercept[ 26].
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