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We assessed all-cause mortality in 127 patients new to hemodialysis assigned to calcium-containing binders or sevelamer after a median follow-up of 44 months from randomization.
Cost-effectiveness analysis only covered three months from randomization.
The study involved three visits and each patient's participation time in the study was not to exceed 6 months from randomization.
After treating three episodes of migraine in no more than 3 months with the second treatment, each patient was asked to assign preference to one of the treatments according to a questionnaire with a preference score graded from 0 to 5. The study involved three visits and each patient's participation time in the study had not to exceed 6 months from randomization.
After treating 3 episodes of migraine in no more than 3 months with the second treatment, each patient was asked to assign preference to one of the treatments according to a questionnaire with a preference score graded from 0 to 5. The study involved three visits and each patient's participation time in the study had not to exceed 6 months from randomization.
Primary outcome: The primary outcome will be change in cIMT over 24 months from randomization.
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Patients will be followed-up every 3 months where Visit 1 is randomization, Visits 2,3,4 and 5 as 3, 6,9, and 12 months respectively from randomization.
With a median follow-up of 39.4 months from first randomization there was a significant increase in median PFS in the R-CHOP group (33.1 vs 20.2 months, P=0.003) without a significant increase in OS at 3 years (82.5% vs 71.9%, P=0.096).
The study will recruit participants over a 3-year period and follow them for a total of 21 months (medication protocols) or 24 months (surgical protocol) from randomization.
At 12 months from time of randomization, 40% of patients in the bevacizumab arm versus 45% in the bevacizumab plus erlotinib arm were progression-free.
In the Langer trial patients were evaluated three and six months after the end of treatment and then every six months until five years from randomization [ 17].
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