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Figure 2 illustrates the nonparametric Kaplan Meier curve estimating the time-to-noncontinuation among the cohort of CD initiators of 6-MP/AZA over time (measured in months from initiation).
Time from starting ART to virological suppression by 12 months was analysed with follow-up censored at the earliest of the following: date of initial suppression, last viral load measurement, and 12 months from initiation.
However disease progression invariably occurs at a median of about 9 13 months from initiation treatment, if acquired resistance commonly due to the development of EGFR T790M mutation.
Two months from initiation of therapy, a follow-up MRI showed a partial response.
Unfortunately, this results in a median survival of only 2 to 4 months from initiation of treatment (5, 6).
Four months from initiation of treatment, her tumors returned in both intracranial and extracranial compartments accompanied by a slight increase in blood flow.
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His OS was 7.7 months from treatment initiation and 20.9 months from initial diagnosis.
Median OS was 9.6 (95 % CI 8.53 10.7) months as from initiation of treatment with azacitidine in the entire cohort.
The 9-month period accounted for the 6-month baseline period and an additional 3 months from dialysis initiation to allow for stability in the CMS claims processing [ 20].
Similarly, in the analysis of LTFU in the second year on ART, person-time accrued from 12 months post ART initiation to the earliest of (1) date of last visit, or (2) date at 24 months from ART initiation, or (3) date of database closure (30 April 2012).
In the analysis for LTFU in the first year on ART, person-time accrued from date of ART initiation to the earliest of (1) date of last visit, or (2) date at 12 months from ART initiation, or (3) date of database closure (30 April 2012).
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