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The developments over the 7 months between groups were then displayed graphically.
There were no significant differences in blood pressure, weight, or waist circumference at 12 months between groups.
9 The SUPPORT trial did not show any difference in death or neurodevelopmental impairment at 18 to 22 months between groups.
Standard methods of economic evaluation alongside a clinical trial [ 51] will be used to evaluate the differences in resource use and health outcomes over 12 months between groups.
The intervention will be implemented over a two month period across all six wards within a group but staggered sequentially every three months between groups.
ACQ scores, asthma-related hospital visits and days off work, oral corticosteroid use and preventer to reliever use ratios will be compared at three and six months between groups.
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To detect a difference of > 0.6 mmol/mol in HbA1c with a standard deviation of 1.2%% at 12 months between group A and B and between group A and C we need 56 per group.
However, the difference in the mean visual acuity at 3 months between Group R and Group N was not significant, which also suggests that a longer time is required for visual acuity improvement.
As the initial focus of the intervention is on the management of depressive symptoms, we have considered the PHQ-9 as a main primary outcome, and will assess changes in PHQ-9 scores over 12-months between groups, adjusting for baseline PHQ-9 score, using a mixed effects multivariate model.
The outcome measures will be compared among baseline, three months, and six months, and between groups.
At 3 months, the between-group difference in anxiety scores, as measured by the GAD-7,was on average, 6.98 units lower than the control group (p = 0.001, 95% CI (1.87, 12.09)).
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agreements between groups
terms between groups
periods between groups
days between groups
hours between groups
period between groups
time between groups
months between inquiries
months between inspections
months between jobs
months between treatments
months between stages
months between months
months between drinks
months between visits
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