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They found for young Chinese children, the high frequency of eating sweets and eating sweets before sleeping are risk factors of caries onset, and decrease of microbial abundance occured 6 months before onset of caries.
Inclusion criteria were age between 18 and 65 years, absence of chronic somatic or psychiatric diseases (other than migraine in the case of migraine patients) and for migraine patients duration of disease at least 1 year, less than 15 days with migraine per month, less than 10 days with acute medication, no prophylactic treatment during the 3 months before onset of the study.
After providing written informed consent (from one of the parents if less than 18 years of age), they answered orally administered standardised questionnaires covering socio-demographic characteristics, present and past health conditions, and exposure to potential risk factors for viral hepatitis in the one to six months before onset of illness.
The piercing was performed 2 months before onset of illness.
Case-patients were asked to consider activities in the 3 months before onset of symptoms.
The premorbid phase is defined as the time from birth until 6 months before onset of psychosis.
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The following data were used to examine the risk factors: gender, age, geographic location, exposure to birds/bird droppings or saprophytes 3 months before illness onset, underlying disease, date of onset of illness, and date of admission.
Recently, MRI-based 3D bone shape has been shown to track concurrently with OA onset, and to predict incidence of radiographic knee OA 12 months before its onset [ 5].
Ten (40%) nonmaternal adult listeriosis cases were receiving chronic corticosteroids at the onset of symptoms, and 6 (24%) had received chemotherapy within 2 months before the onset of listeriosis.
To minimize the developmental disruption associated with schizophrenia, much work has recently been done to identify and treat the prodromal (pre-onset) phase of the illness, which has been detected up to 30 months before the onset of symptoms.
The following data were extracted from the patients' medical records: gender, date of birth, residential area, rural or urban residence, occupation, marital status, date of onset and allergic history, family medical history, childbirth history, and disease history within 2 months before the onset of ADEM.
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