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The poor outcome (PO) at 1 month, defined as a modified Rankin Scale score of 3-6, was the primary end point.
The primary outcome is continuous abstinence from smoking at one month, defined as not smoking more than five cigarettes since quit date.
Physical activity (none, 1 4 times a month, or more than 4 times a month) defined as taking part in any sports, exercises, or vigorous leisure activities in the month preceding the interview at both 43 and 53 years.
Treatment-failure after 1 month, defined as a drop-out from the blinded phase due to inefficacy and request for an active treatment injection, was 2.5-times higher in the placebo vs. the BoNT/A group; 45% (10/22) vs. 19% (4/21; p = 0.128) respectively.
1 On average, 87% of students reported drinking alcohol at least once in their lifetime, 57% reported drinking alcohol in the past month, and 39% reported heavy episodic drinking in the past month (defined as 5 or more drinks on one occasion).
A simple mixed-effects model with only a random intercept and a fixed slope for the linear change in (log) BDE-47 over time since birth yields an estimated 3% decline in BDE-47 per month, with a 95% confidence interval (CI) of 2 4% decline per month (defined as 30 days; p < 0.001), using a robust method to calculate the variance of the estimated slope.
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To examine activity patterns of individuals, we included day-type (weekday vs. weekend), season (May to October defined as warm season vs. November to April as cool season, according to the climate in California), the time variable (1st-6th wave), sex, and age as covariates in the model.
Wind speed data reveal that the windy months in Waterloo are from November to April, defined as the Cold Season in this study, with February being the windiest month.
A supplementary decree issued in November defined as Jewish anyone with three Jewish grandparents, or two grandparents if the Jewish faith was followed.
The unit of analysis was the patient care unit-month (abbreviated as unit-month) defined as data aggregated by month for each patient care unit.
The patient care unit-month, defined as data aggregated by month for each patient care unit, was the unit of analysis (N = 1063).
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