Exact(2)
Furthermore, we decided to compute a second model which was adjusted for age, gender, number of days with intake of acute medication per month, adherence to pharmacological prophylaxis, PMR, and aerobic endurance sports as potential confounders.
Other variables included the Charlson Comorbidity Index (CCI); a normal A1c rate over the past 12 months based on laboratory test results (normal A1c rate); 12 month adherence to clinic schedules (adherence rate); and the experience of a prior year hospitalization.
Similar(58)
The moderation effect was not significant for the SDSCA item regarding adherent days or the 1-month adherence self-ratings.
In these cases, the previous month's adherence was used in calculations of single-month adherence (e.g., month 11 was used for month 12 adherence).
As opposed to the geriatric assessments and care plans, overall first 6-month adherence to MTC delivery was low but increased over time.
Antidiabetic medication use (i.e., oral mono- or combination therapy) was also assessed at the time of sustained hyperglycemia, as was the patient's recent 6-month adherence to this therapy.
In this retrospective chart-review, 6-month adherence to antidepressants was examined in 367 outpatients with a major depressive disorder (ICD-10) (170 males; mean ± SD age 37.6 ± 13.9 years), who started antidepressant treatment from April 2006 through March 2007.
A retrospective analysis of pharmacy claims in a database of more than 64 million members enrolled in 100 health plans assessed persistence and adherence to drug therapy in 6 chronic conditions including type 2 diabetes: 12-month adherence rate for oral antidiabetic drugs was 72%, and as low as 40% at 2 year [ 10].
We have assumed that all those collecting a prescription for a statin medication have in fact taken the medication as prescribed, although it has been estimated that 12-month adherence rates to statins are around 60%, with the risk of non-adherence reducing with increasing age [ 14, 27].
Assuming a similar ICC and attrition rate for other outcomes, this sample size will have 99% power to detect a 1 SD difference in any continuous measure (e.g., approximately a 2-point difference in a 10-question knowledge scale), and 80% power to detect a 30% difference in 6-month adherence rates assuming a control adherence rate of 50%.
This finding contrasts with the findings of King et al. (13) that home-based exercise training participants had better 12-month adherence rates than community facility based participants and suggests that the home-based BDPPI participants did not receive sufficient ongoing support to maximize adherence.
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