A important issue with the circularization bias is that it is highly non monotonous: for example, it favors circularization lengths of 261 bp, but disfavors circularization length of 266 bp and again favors circularization lengths of 271 bp and so on and so forth (see inset in Figure 1D).
Non-stationary noise to other non-monotonous noises, for example, children shouting in a kindergarten.
The synthetic polymers in the plastic skin of a garbage bag, for example, are monotonous skeins of a single type of chemical bauble, ethylene, while the protein polymers in a fish's skin are intricate arrays of as many as 20 distinct amino acids, the monomers of which proteins are built.
My life often feels monotonous and monotone.
All subjects were employed in jobs with monotonous and repetitive work tasks, for example, assembly line work and office work.
(His examples included the phrases "monotonous climate" and "beautiful autumnal colours"). Our sample is limited, but the only instances in which we observed such complaints were about papers authored by women.
Each stop along the route is so richly fleshed out that the book never suffers from the monotonous, episodic quality that typifies lesser examples of this genre.
Through numerical examples, we elaborate on the monotonous properties of the performance measures, and draw the insights into the impacts of the system parameters on its various performance indices, which provide important guidance for design of assembly systems.
Even cost functions that do not follow monotonous mathematical rules may apply, as illustrated by the example in Duan and Mage [ 42], where the basic shape of the cost function changes with the number of measurements, and by some examples in Cochran's excellent textbook [ 47].
Examples of these physical work demands are monotonous and repetitive arm movements, awkward body postures, prolonged standing, work with arms above shoulder height, and heavy lifting [ 11].
