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Safety assessments included monitoring electrocardiogram outputs, heart rate, blood pressure and toxicology indices in cynomolgus monkeys administered with AZD9773.
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In one test, monkeys administered thirty times the sleep dose of dora-22 showed no impairment after being woken and given an attention test.
After 2.5 h of atipamezole injection (approximately 3 h after tetrodotoxin injection), the monkey was administered with ketamine (6 mg/kg, i.m).
Control mice were administered with plain PBS.
These bacteria have been found to be safe in mice, pigs and monkeys when administered intravenously.
Adult Rhesus monkeys were administered repeat intravenous doses of AGT-181 ranging from 0.2 to 20 mg/kg.
Young adult cynomolgus monkeys were administered cuprizone per os as a dietary supplement.
As a result of problems with access to SurveyMonkey, we administered this wave via REDCap, an alternate secure, online application for managing surveys.
After tetanus was diagnosed in the monkeys, we immediately administered tetanus vaccine to monkey caretakers at the facility and thoroughly enforced hygiene practices.
administered orally with food.
In their study, pregnant nonobese rhesus monkey females were administered testosterone from days 40 to 80 of the typical 170-day gestation, with testosterone levels increasing from 0.03 to 0.3 0.4 ng/ml.
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