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This monitoring schedule is outlined in Table 1.
While certain logistical aspects of clinical practice (ie, high patient volume, lack of support, etc) may influence clinicians' attitudes towards these two aspects of the T2T recommendations, some participants also commented that a tight monitoring schedule is not necessary as long as the patient is showing improvement (data not shown).
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Even when monitoring schedules were adhered to, the proportion of patients with severe hepatotoxicity was very low.
Another important issue that needs to be considered in monitoring the project schedule is that the critical path may be changed during the project execution.
A regular and frequent monitoring schedule should be developed, taking care to obtain input from the adolescents and families to ensure compliance with the monitoring strategy [ 13, 44].
ART medication was started thereafter and the adherence to the pill intake schedule was monitored by means of using electronic monitors and self-recording for a period of 6 weeks.
The environmental temperature and lighting schedule were automatically monitored every 5 min throughout the experiment.
It is also of importance to note that in some European countries a more flexible monitoring schedule, which can be reduced to quarterly blood testing in individuals not at risk, has been proposed [ 59, 60].
According to the program monitoring data, the provider's busy schedule was the most commonly cited reason for not participating in the seminar or the educational visits.
The planned sensitivity analyses based on methodological quality, population characteristics, and monitoring schedule could not be performed because of the small number of studies and the methodological weaknesses inherent in included studies that would have made interpretation of such a subgroup analysis speculative.
22 The cross-sectional nature of the current investigation, coupled with the required anonymised recruitment process, made it impossible to determine where each patient was with regard to both their PSA monitoring schedule and how long ago were they diagnosed.
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