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To improve environment monitoring, the proposed framework allows developers to design monitoring rules, in LINC, and create soft sensors from physical sensors.
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Application of the monitoring rules, illustrated in Figure 4, shows that the frequency of CD4 determinations can be kept low while high counts are observed.
On the other hand, aggressive monitoring rules may result in an early termination for futility when the experimental arm is doing better than the control arm (in some cases nontrivially better, especially when trials are designed for unrealistically large effects).
For that, they write specific LINC rules called monitoring rules.
Agree to certain monitoring rules around the account.
The designed monitoring rule templates were instantiated in specific rooms.
In summary, compared with the Simon optimal two-stage designs, our proposed BHT-A design can terminate trials of unpromising doses early, by utilizing a continuous monitoring rule and nonlocal alternative prior distributions in the hypothesis tests.
In both designs, we implement a separate continuous monitoring rule for toxicity.
Listing 5 presents an example of monitoring rule template.
Striped Bass is a very well regulated fishery with fishermen closely monitored to the rules in place.
The costs of administering this intervention may be high due to the difficulty of distant government agents to effectively monitor and enforce rules in a community (Bloom et al. 2011 ).
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