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Monitoring of trough levels of fluconazole was not routinely performed in our hospital.
Dosage tailored to gestation with monitoring of trough concentrations remains management of choice.
Monitoring of trough concentrations is necessary after the forth dose to maintain serum trough concentrations of 15-20 mg/L increase efficacy and improve clinical outcomes.
The monitoring of trough concentrations to prevent nephrotoxicity is recommended (i.e., sustained troughs of 15 20 g/mL), especially in patients with unstable renal function or therapy for longer than 3 5 days [ 33, 34].
This could be explained by standard "precautions" shared by both ICUs, including short-term use of aminoglycosides under daily monitoring of trough levels and a restrictive prescription policy of NSAIDs and drugs acting on the renin-angiotensin pathway.
In a minority of patients, an increased frequency of administration may be required; the monitoring of trough plasma levels at 5-6 h could identify such patients, particularly if they are not clinically responding to stress doses of hydrocortisone.
Similar(53)
With this aim, therapeutic drug monitoring (TDM) of trough levels might be a useful tool for refining dosing decisions during the maintenance phase of therapy, as it is routinely performed with aminoglycosides and glycopeptides.
Outcome may be improved by adequate monitoring of vancomycin trough levels.
Our results suggest that the treatment strategy for persistent staphylococcal bacteremia with rifampin may be effective, but can be optimized by improving the monitoring of vancomycin trough levels and minimizing the delay in starting rifampin treatment.
TAC might be superior to CyA with regard to the lack of need for frequent monitoring of the trough concentration, particularly when using these drugs in the outpatient clinic.
TAC might be safely usable at or below 3 mg/day, which is officially approved as a standard dose, in PM/DM without frequent monitoring of the trough concentration as long as renal function is almost normal.
Related(20)
monitoring of dip
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monitoring of anyone
monitoring of system
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monitoring of lending
monitoring of progress
monitoring of tissue
monitoring of shape
monitoring of activation
monitoring of sex
monitoring of water
monitoring of groundwater
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