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Our study, thus, for the first time gives an insight into the real-time cell monitoring of action for antibacterial agents.
One promising area of application for GECIs is in all-optical monitoring of action potentials.
This describes an umbrella term for functions such as planning, working memory, inhibition, mental flexibility, as well as the initiation and monitoring of action.
This allows simultaneous monitoring of action potential-induced calcium signals in a plane (Ohki et al. 2005) or volume (Göbel and Helmchen 2007) of tissue.
If so, reality monitoring of action memories would be predicted to elicit activity in medial PFC regions similar to those identified previously.
Turning to brain regions with a particular role in memory for actions, greater activity during reality monitoring of action memories than for location recollection was observed in left ventrolateral PFC and supplementary motor area.
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Beyond these unconscious adjustments the central monitoring of actions is fundamental for the indication of errors (Ridderinkhof et al., 2003) and for the conscious determination if sensory input was generated by the acting subject itself or by another agent.
Recent electrophysiological studies have suggested deficits in response monitoring and a diminished capacity to monitor error responses in children with ADHD, represented by decreased amplitudes of the ERN over the ACC, a region which is important for the discrimination between stimuli and the monitoring of actions and errors [ 25].
Note that the behavioral results included no significant study or test condition differences in terms of recollection accuracy, and significantly slower reaction times during reality monitoring of actions that had previously been imagined than for actions that had previously been performed.
Whereas both strategies induced a similar activation in the motor regions of the brain, implicit imagery was associated with a lower activation in the ventromedial prefrontal cortex, reflecting the decreased self-monitoring of actions that occurs in this case.
Further, although during audit feedback there was a problem-solving session with an action-plan developed, hardly any action was subsequently implemented and there was insufficient monitoring of proposed action.
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