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Engineering of optical captors allows facile and reliable signaling in continuous monitoring modes, and enables simple and high-speed removal of toxic chromium (VI) ions.
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MS detection was realized in multiple reaction monitoring mode, and the carbonyl compound concentration (expressed in μg/cigarette) was calculated using an external calibration curve.
The analytes were detected in ESI+ with multiple reaction monitoring mode and fragmentation conditions were optimized to obtain the highest sensitivity.
The method was based on selective liquid/solid extraction, combined with liquid chromatography electrospray ionization tandem mass spectrometry in the multiple reaction monitoring mode and negative ionization.
Analysis was carried out using the dynamic multiple reaction monitoring mode and fast polarity switching.
Compounds were analyzed in multiple reaction monitoring mode and quantified by using surrogate corrected calibration curves.
Figure 4A and B shows the chromatograms acquired in total ion monitoring mode and processed to the responses of peaks at m/ z 444 and 412, respectively.
Acquisition was performed in the selected reaction monitoring mode and the chromatographic run was divided into two individual periods with a settling time of 50 ms.
Quantitation of absolute protein and mRNA levels in central carbon metabolism was accomplished by liquid chromatography tandem mass spectrometry in a multiple reaction monitoring mode and real-time quantitative polymerase chain reaction (PCR) methods, respectively [ 3].
The samples were analyzed for 64 organic compounds, including pesticides, polycyclic aromatic hydrocarbons, and polychlorinated biphenyls (PCBs), using GC/MS in multiple ion monitoring mode; and for nine metals using conventional microwave-assisted acid digestion combined with ICP/MS.
The mass spectrometer was operated in targeted multiple reaction monitoring mode and each urine sample was analysed twice, first, in positive ion mode for drugs and metabolites listed in category 'Positive' in table 1 and then in negative ion mode for those listed under 'Negative' in table 1.
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