1 The aims may be to detect recurrence of tumour, to monitor late effects of treatment, to collect data and to offer patients an opportunity to raise concerns or anxieties arising from their cancer.
Conan O'Brien Shows monitored: "Late Show With David Letterman" (CBS); "Tonight" with Jay Leno (NBC); "Late Night" with Conan O'Brien (NBC).
One has to note that expression changes were monitored late after infection (7 weeks after inoculation).
Integration of novel molecular prognostic markers, the role of HSCT in first remission, treatment strategies for relapsed/refractory disease and monitoring and timely intervention of late effects require addressing in future trials.
Ultimately, to improve the outcome for infants with ALL, key areas still to be addressed include identification and adaptation of novel prognostic markers and innovative therapies, establishing the role of hematopoietic stem cell transplantation in first complete remission, treatment strategies for relapsed/refractory disease and monitoring and timely intervention of late effects in survivors.
Detailed discussion of these issues is beyond the scope of this review, although we have made some rudimentary suggestions for late effect monitoring.
A monitoring program to check for the late effects of treatment, like heart damage, thyroid disorders or bone marrow disease.
Because aggressive surgical resection is the recommended optimal therapeutic strategy for child and adolescent meningioma, 6 our study further highlights the importance of monitoring and time-appropriate intervention for late effects in survivors of childhood brain tumors for whom surgery is the mainstay of treatment.
If late effects were indicative of retrieval monitoring, then we would expect negative repetition effects only for the conditions that initially involved retrieval monitoring on the first presentation.
Our study has also demonstrated the utility of routinely collected, linked hospitalisation records for high level monitoring of many serious, though not necessarily fatal late effects at a relatively low cost.
