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Some participants actively searched for information about the benefits and safety of HDS and experimented with HDS by monitoring efficacy and adverse effects.
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Independent Data and Safety Monitoring Committees were established to monitor efficacy and safety data.
The purpose of this committee will be to monitor efficacy and safety end points.
This study demonstrates the potential of using validated pharmacodynamic circulating cell death biomarkers to monitor efficacy and toxicity in patients with HL.
The purpose of this committee will be to monitor efficacy and safety end points, although only independent members will have access to un-blinded study data.
In addition to the above, the DMC will monitor efficacy and safety outcomes and will provide the trial's Steering Committee with recommendations regarding continuing or stopping the trial (for all patients or subgroups of patients) when approximately 25% (safety only), 50% (safety and efficacy) and 75% (safety and efficacy) of the anticipated outcome data are available.
IGFBP3 is less sensitive to short-term nutritional variations and diseases than IGF-I and could therefore be valuable when monitoring efficacy of and compliance with GH treatment [ 38].
Both EGFR-TKIs, for which [18 F]FDG-PET as already demonstrated utility in monitoring efficacy [8], and MEK/Raf inhibitors are targeting the MAPK pathway.
Direct costs included drug-acquisition costs for chemotherapies, premedication, adverse-event treatment and monitoring, efficacy evaluation, BSC, drug administration, and follow-up tests during remission.
There is a need therefore to develop more specific tracers for both predicting and monitoring efficacy of chemotherapy.
From the monitoring efficacy, the high precision and good practical application have emerged.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com