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The combination offers an excellent system for monitoring cell development and cell-drug interactions.
This new approach allows monitoring cell development and cell-drug interactions with minimal perturbation of the biological system of interest.
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Researchers have long-desired to look at chemical information to monitor cell development or cell-drug interaction in the cell's natural state.
This hypothesis was confirmed by monitoring B cell development in knockin (KI) mouse models carrying V (D) J rearrangements identical to those of the mature bNAbs 2F5 and 4E10.
We monitored cell death development in infected leaves of npr1 single and atg5 npr1 double mutants.
Because class II is important for T cell development [14], we monitored populations of CD4 and CD8 negative, single positive and double positive T cells isolated from the thymus.
It contributes to blood cell development.
At present, the development of an effective visualization tool to monitor cell death remains a significant challenge.
Monitor cell interactions.
By depleting both maternal and embryonic Sox2 mRNA at the 2-cell stage and monitoring embryo development in vitro we show that, in the absence of Sox2, embryos arrest at the morula stage and fail to form trophectoderm (TE) or cavitate.
By depleting both sources of Sox2 mRNA at the 2-cell stage and monitoring embryo development in vitro, we showed that in the absence of Sox2, embryos arrest at the morula stage, and they fail to form TE or to cavitate.
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