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These results emphasize the reliability and validity of measurement of WT1 transcripts for MRD monitoring and relapse prediction.
This paper first reviews the clinically used non-FDG radiopharmaceuticals for PET and SPECT imaging, respectively (Table 1), and discusses their advantages and limitations in staging, treatment monitoring, and relapse surveillance in lymphoma patients.
To address these issues in gastric cancer, we investigated the clinical usefulness of the NY-ESO-1 humoral immune response for diagnosis, monitoring, and relapse prediction in gastric cancer patients.
Real-time PCR of peripheral blood, using reagents specific for a patient's particular antigen receptor gene rearrangement, has also been used for remission status monitoring and relapse detection in canine LSA [ 43, 44]; however, this is labor and time intensive and requires the generation of custom tools for each patient, and would also not be suitable as a screening test.
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It aimed to support increases in physical activity through a range of self-regulatory skills including goal setting, action planning, self-monitoring, and relapse prevention.
Ethyl glucuronide in hair (hEtG) and serum carbohydrate deficient transferrin (%CDT) are valuable markers for alcohol abuse, but their diagnostic accuracy to monitor abstinence and relapse is unclear.
These data prompt us to propose that CD105 is an angiogenic marker that can be used for monitoring tumour metastasis and relapse.
Bioluminescence imaging has been shown to be sensitive in various animal studies and has also been used to monitor tumour progression and relapse [13].
As such, the reported potential utility of circulating nucleosome quantification has been limited to monitoring therapy efficacy, including radio- and chemotherapy in pancreatic cancer [ 14, 15] and relapse monitoring.
Additionally, blood-based diagnostics can classify tumours into distinct molecular subtypes and monitor disease relapse and response to treatment (Hanash et al, 2011).
The only clinically validated biomarker for disease monitoring and assessing response and relapse to treatment is CA125 which is encoded by MUC16 mucin gene [ 7– 12].
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