Executive function can be divided into at least three separable components, including set shifting, attentional updating and monitoring, and inhibition of prepotent responses.
In the second part of the article, we describe an integrative neuro-computational account of action simulation, which links the neural substrate (as revealed in neuroimaging studies of action simulation) to the components of a computational architecture that includes internal modeling, action monitoring and inhibition mechanisms.
16 Executive functions, which include monitoring and inhibition, are essential roles that are played by the frontal lobe.
The Stroop task is frequently employed to assess high-demand cognitive processes including attentional and executive control, stimulus conflict, response monitoring, and inhibition with well described behavioral effects and neural basis (27,28).
Secondly, the prefrontal cortical regions form part of an extended motor network (for a review, see Rowe and Siebner, 2012), with activation occurring during many motor tasks including attention, selection, planning, monitoring and inhibition of action, conscious motor intentions, goal-directed and novel movements.
Here, an enzyme-assisted amplification strategy was developed for the ultrasensitive monitoring activity and inhibition of T4 PNK.
The method not only provides a platform for monitoring activity and inhibition of exonuclease but also shows great potential in biological process researches, drug discovery, and clinic diagnostics.
Therefore, it provided a promising platform for monitoring activity and inhibition of PNK as well as for studying the activity of other nucleases.
Results showed that the efficiency of the aforementioned cognitive mechanisms was positively related to the frequency of saving behaviors that required monitoring, integration, and inhibition to be implemented in daily behaviors and routines.
This novel method not only provides a promising platform for monitoring activity and inhibition of DNA MTases, but also shows great potentials in biological process researches, drugs discovery and clinical diagnostics.
This developed Exo III cleavage-induced DNAzyme releasing strategy opens a promising avenue for monitoring activity and inhibition of nucleotide kinase, and should be also conveniently used for the sensor of other proteins or nucleic acid and may have widespread applications in biological process researches, drug discovery, and clinic diagnostics.
