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Circularly-permutated versions of GFP (cpGFP) have successfully been used to monitor structural rearrangements of calmodulin (Baird et al., 1999; Nagai et al., 2001; Nakai et al., 2001; Wang et al., 2008; Akerboom et al., 2009).
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We rationalized that it may be possible to create transport activity sensors by monitoring structural rearrangements in a transporter with the help of environmentally sensitive genetically encoded fluorophores.
As a more direct route, strong segregation distortions induced by structural rearrangements can also be monitored using small-sized progenies 30-500 individuand) and be subjected to the neighbor joining approach that we have used.
Wang, H. et al. Cryo-EM structure of a CD4-bound open HIV-1 envelope trimer reveals structural rearrangements of the gp120 V1V2 loop.
Simulated structural rearrangements in the sugar-bound state.
G. Structural rearrangements underlying K+ channel activation gating.
There are also structural rearrangements going on behind the scenes.
The structural rearrangements showed to achieve the outward-facing state were extensive.
Mauve 2.349 was used to identify structural rearrangements and inversions throughout the strain's genome.
Structural rearrangements, SNV mutations, and CN abnormalities were called to identify key MM driver genes.
The structural rearrangements and molecular events leading to lid closure are still unknown.
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