Pigs were monitored for evidence of infection for 21 days following exposure, i.e., serum samples were collected on days 0, 7, 14, 21, and tested for virus and PRRS virus-specific antibodies.
Transgenic and non-transgenic progeny were monitored for evidence of neoplasms (Table 2).
Mice were routinely monitored for evidence of disease and moribund mice were sacrificed.
Due to reports of myo- and pericarditis following vaccination with live replicating vaccinia virus [12], [13], subjects were also monitored for evidence of cardiac abnormalities.
All animals were monitored for evidence of CWD infection by serial tonsil biopsies taken at 3, 6, 12 months pi, and at study termination.
All animals, housed and handled in strict accordance with good animal practice under supervision of veterinarians, received environmental enrichment and were monitored for evidence of disease and changes in attitude, appetite, or behavior suggestive of illness.
All animals were closely monitored for evidence of clinical illness (temperature, respiration, anorexia, dehydration, central nervous system disturbances, reduced activity and changes in behavior, and changes in complete blood count and chemistry) following NiV challenge.
During this period, mice were monitored for evidence of leukaemia.
Mice were monitored for evidence of tumor growth by inspection and palpation.
