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Monitor for efficacy, tolerability, and safety.
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This approach can allow many animal models of localized infections to be accurately monitored for efficacy of treatment by PDT.
Tumour growth was monitored for efficacy and a survival endpoint (for the Kaplan Meier graph) was introduced when individual tumour volume reached 400 mm3.
Thall and Simon's method was employed to perform continuous interim monitoring for efficacy [ 12].
Medicines often require patient monitoring, for efficacy and adverse events, sometimes involving laboratory measurement of their effect (e.g. international normalized ratio for warfarin).
Thus, to ensure the safety of new PF products, phase IV post-licensure safety surveillance studies must be conducted to monitor products for efficacy as well as for rare, adverse events.
Moreover, many studies suggest that ALP may be a tumor-associated antigen and a monitor for drug efficacy in serum [34]– [34].
Patients should be monitored regularly for efficacy and tolerability, whether by visit, by phone, or by email, especially within the first weeks of treatment.
Scenario analyses investigated whether laboratory monitoring (CD4+ tests for efficacy monitoring; haematology/biochemistry for toxicity) could be tailored and targeted to be delivered cost-effectively.
Many MDA programs now require monitoring for drug efficacy as a key component.
Monitoring for anticoagulant efficacy has some unique practical consequences (particularly for CRRT) that often limit effective use of these therapies.
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