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The total and ANA sub-serology tests also facilitate differential diagnosis and its refinement [1], predict incipient disease [2], indicate disease severity or impending flares [3], serve as prognostic markers for further organ involvement [4], monitor efficacy of therapy [5], and asses induction of autoimmunity by drugs [6].
Such bright cells can be effectively used to monitor efficacy of drug candidates in models of metastasis and orthotopic tumor models, to track metastatic migration of cancer cells, and can be also utilized to accurately ascertain whether any residual disease remains following the treatment.
The purpose of this committee will be to monitor efficacy and safety end points.
Independent Data and Safety Monitoring Committees were established to monitor efficacy and safety data.
The assay is suitable for use in clinical trials to monitor efficacy or pharmacodynamic effects of drug candidates.
Being a critical step in the cardiovascular continuum, endothelial function may serve as a surrogate marker to monitor efficacy of treatment.
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There is a need therefore to develop more specific tracers for both predicting and monitoring efficacy of chemotherapy.
From the monitoring efficacy, the high precision and good practical application have emerged.
Sixty-one patients with non-small cell lung cancer (NSCLC) who were scanned for monitoring efficacy of chemotherapy, molecularly targeted therapies or radiotherapy were included.
Both EGFR-TKIs, for which [18 F]FDG-PET as already demonstrated utility in monitoring efficacy [8], and MEK/Raf inhibitors are targeting the MAPK pathway.
A key limitation in the demonstration of monitoring efficacy in neurocritical care is the complexity of treatment generated by multimodality monitoring.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com