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In optogenetics, light-activated proteins are used to monitor and modulate cellular behaviour with light.
We have developed a novel, low-cost device designed to monitor and modulate locomotor activity in murine subjects.
Singleton A, Khong D, Chin LY, Mukundan S, Li M, Parekkadan B. An engineered biomarker system to monitor and modulate immune clearance of cell therapies.
Both of these intrabodies colocalize with H-Ras, K-Ras, and G12V mutants inside the cells, providing new potential tools to monitor and modulate Ras-mediated signaling.
This allow us to precisely monitor and modulate H2O2 levels inside compartments and sub-compartments of the living cells, in a cell- and tissue-specific way.
A second team at the University of Pennsylvania (UPenn) will receive up to $22.5 million to develop a device that can monitor and modulate many different brain regions involved in memory formation and storage.
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In CSC, the 'semantic control' system, underpinned predominantly by the prefrontal cortex, dynamically monitors and modulates the 'semantic representation' system that consists of a 'hub' (anterior temporal lobe, ATL) and multiple 'spokes' (modality-specific areas).
Ligands that specifically target individual subunits provide new tools for monitoring and modulating these networks, but are challenging to design due to the high sequence homology and structural plasticity of the Gα-binding surface.
For more than a decade, Lieber pioneered the field of nano-bioelectronics, creating nanowire electronic devices with powerful new capabilities for ultra-sensitive, real-time detection of cancer markers and viruses, as well as the first nanoscale transistor tools capable of monitoring and modulating the behavior of individual living cardiac and neuron cells.
In particular, he has led the field of nano-bioelectronics, creating nanowire electronic devices with powerful capabilities for ultra-sensitive, real-time detection of cancer markers and viruses, as well as the first nanoscale transistor tools capable of monitoring and modulating the behavior of individual cardiac and neuron cells.
Thus, host immune and inflammatory responses need to be carefully monitored and modulated during treatment to prevent inflammatory injury.
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