Your English writing platform
Discover LudwigSuggestions(1)
Exact(2)
With combination of EMSA and biosensor, a qualitative and quantitative method is described, which can be extended to studying the binding of most small molecules with targeting DNA and serves as a powerful tool in designing and screening for novel drugs.
These hybrid probes include small molecules with targeting groups that interact with specific enzymes and genetically encoded proteins whose signal output is modulated by binding of a small-molecule fluorophore.
Similar(58)
Over 700 molecules with target related information from the literature were curated for use in CDD and TB Mobile.
Future methods may use more predictive machine learning models [56, 58] but will require expansion of the training set of molecules with targets.
An additional 60 molecules with target related information from the literature (Additional file 1: Table S1) were curated for use in CDD and TB Mobile.
C-probes are linear molecules with target-specific termini separated by an internal spacer sequence or core and have been described by us [ 1, 13] and others [ 14– 17].
At the core of the emerging field of synthetic biology resides, our capacity to design and reengineer molecules with target functions.
Pharmaceuticals in the environment have ecotoxicological effects on some nontarget species that have the same active sites, such as organs, tissues, cells, and active molecules with target species [ 91].
Inhibition of this pathway has been shown to be potentially advantageous compared with β-blockers, the conventional therapy for CPVT patients; however, the use of CaMKII inhibitors in the clinical setting is still limited by the lack of molecules with target- and tissue-specificity.
RNAi molecules are encapsulated in a lipid bilayer with targeting molecules facing outwards to bind to receptors of interest.
The outer shell of the nanoparticles consists of another polymer, PEG, embedded with targeting molecules that guide the particles to the correct destination.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com