Sentence examples for molecules with target from inspiring English sources

Over 700 molecules with target related information from the literature were curated for use in CDD and TB Mobile.

An additional 60 molecules with target related information from the literature (Additional file 1: Table S1) were curated for use in CDD and TB Mobile.

At the core of the emerging field of synthetic biology resides, our capacity to design and reengineer molecules with target functions.

Pharmaceuticals in the environment have ecotoxicological effects on some nontarget species that have the same active sites, such as organs, tissues, cells, and active molecules with target species [ 91].

Inhibition of this pathway has been shown to be potentially advantageous compared with β-blockers, the conventional therapy for CPVT patients; however, the use of CaMKII inhibitors in the clinical setting is still limited by the lack of molecules with target- and tissue-specificity.

With combination of EMSA and biosensor, a qualitative and quantitative method is described, which can be extended to studying the binding of most small molecules with targeting DNA and serves as a powerful tool in designing and screening for novel drugs.

Future methods may use more predictive machine learning models [56, 58] but will require expansion of the training set of molecules with targets.

C-probes are linear molecules with target-specific termini separated by an internal spacer sequence or core and have been described by us [ 1, 13] and others [ 14– 17].

These hybrid probes include small molecules with targeting groups that interact with specific enzymes and genetically encoded proteins whose signal output is modulated by binding of a small-molecule fluorophore.

This new technique allows structural biologists to visualize how specific molecules interact with target proteins in cells, and how protein mutations affect cell function.

They can also be used to explore the target structures for possible active sites, generate candidate molecules, dock these molecules with the target, rank them according to their binding affinities, and further optimize the molecules to improve binding characteristics [ 25].