Sentence examples for molecules with reduced from inspiring English sources

Further experiments revealed that while these antibodies preferentially bind to mono and unglycosylated PrP, they also bind to diglycosylated molecules with reduced binding strength (e.g. in Supplementary Figure S4A).

Improvements in the ADME profile were realized by designing more ligand-efficient molecules with reduced molecular weights and lower lipophilicities.

In this contribution, using theoretical methods we demonstrate the importance of these factors in the surface-confined self-assembly of tripod-shaped organic molecules with reduced symmetry.

The present study carried out with this pilot library of 32 compounds will provide us with necessary information for designing antitubercular molecules with reduced MAO-inhibitory activity and also help us in identifying a selective MAO-B inhibitor which has potential clinical utility in neurodegenerative disorders.

With the identification of FGFR4 as the receptor mediating the induction of hepatocyte proliferation but not the improvement in glucose tolerance, it was predicted that FGF19-like molecules with reduced FGFR4 activity should provide metabolic benefits without causing unwanted side effects.

Normally, GSTs catalyze the conjugation of toxic molecules with reduced glutathione (GSH) and target them for ATP-dependent transport into the vacuole.

The glycating power, that is, the abilty of different molecules with reducing carbonyl groups to interact with the amino group of a proteins is strongly dependent on their molecular structures and electronic properties.

The results presented in the current paper also indicate that it may not be sufficient to include a control without cells in the MTT assay, a stratagem that has been recommended to avoid false-positive results in the presence of molecules with reducing properties, such as flavonoids [ 18].

The concepts and recent developments including the activation of dioxygen molecule with reducing agents are summarized with emphasis on the catalytic oxidation of inactive hydrocarbons.

The addition of the BODIPY-FL fluorophore resulted in molecules with much reduced potency, which was probably due to a reduction in affinity, as no binding was detectable.

A common end to numerous pathways that lead to defective sperm function is attributed to reactive oxygen species (ROS), a group of molecules with incompletely reduced oxygen atom [ 10, 11] that are capable of reacting with almost all biomolecules leading to their altered function such as inhibition/activation of enzymes.