Sentence examples for molecules with improved from inspiring English sources
Decades of studies have led to the development of modified protocols that recapitulate molecular developmental cues by combining various growth factors and small molecules with improved efficiency.
Together with large-scale mining of activity or physicochemical data, matched molecular pair analysis (MMPA) has the potential to aid the design of molecules with improved properties by highlighting favourable transformations.
It should also be possible to develop an understanding of how to manipulate rationally the structure of these compounds so as to generate molecules with improved in vivo characteristics.
A useful heterologous production system is required to obtain sufficient amounts of recombinant therapeutic proteins, which are often necessary for chemical characterization and engineering studies on the development of molecules with improved properties.
Atomic substitutions and additions in the side groups of PPG were made using the Osiris program to design molecules with improved drug like properties, better selectivity, and higher binding affinity to Plk1.
Based on these results, novel molecules with improved activity can be designed.
Compound 1e emerged as the most interesting of this series, showing a multipotent biological profile and suggesting that conjugation of an appropriate coumarin core with a properly selected butynyl-amino chain allows to obtain novel hybrid molecules endowed with improved in vitro antitumor activity.
These concentrated and enhanced electromagnetic fields can excite fluorescent molecules with highly improved fluorescence efficiency.
The results from this study provide further evidence that analogs of the sesquiterpene MMB can be designed to afford molecules with significantly improved anticancer activity.
These findings further emphasize ADCC as an important factor for mAb activity, providing the rationale to apply protein engineering technology to generate new molecules with significantly improved potency.
The small organic molecules or peptides need to bind the protein targets but only with modest affinities and selectivities, because conjugation to the polypeptides results in molecules with dramatically improved binder performance.
