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The screens identified molecules with both broad and narrow inhibition profiles, proving that protein kinase inhibitors offer privileged chemical matter with the potential to block antibiotic resistance.
Many of the RAGE ligands represent a unique class of molecules with both intra- and extracellular activities [ 14, 15].
For these countries, the retail channel (IMS) has more molecules with both an originator and at least one generic available than the procurement channel (GPRM).
Transcription factors represent "master switch" genes, which regulate expression of differentiation-related molecules with both structural and functional specificity, and, thus, mediate metaplasia.
Sphingolipids are lipids based on sphinganine or sphingosine that form a large family of molecules with both structural and signaling functions [ 14].
The rCII that is routinely used for immunization is derived from Swarm chondrosarcoma - a tumor cell line that produces collagen molecules with both hydroxylated and glycosylated residues [ 28].
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Such magnetic microspheres can be utilized as sensitive surface-enhanced Raman scattering (SERS) substrates, using Rhodamine 6G (R6G) as a probe molecule, with both stable and reproducible performances.
Finally, we show that the simultaneous interaction of a single Rad4TopBP1 molecule with both Thr187 phosphorylation sites in a Crb253BP1 dimer is essential for establishing the DNA damage checkpoint.
The results of a first-principles study based on density functional theory on the interaction of Melamine molecule with both defected and defect free graphene nanoribbons(GNRs) are reported.
This hyperchromic effect was evident for the successful conjugation of the chromophoric ROS molecule with both BSA and KLH.
The methanol fraction showed a 6.5-fold increase in activity compared to E. coli conditioned medium, again, suggesting a molecule with both lipophilic and hydrophilic portions [31].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com