Sentence examples for molecules with anticancer from inspiring English sources

DNA is considered one of the most promising targets of molecules with anticancer activity potential.

The search for such potential anticancer drugs has led to the discovery of synthetic molecules with anticancer activity.

Some molecules with anticancer activity that act against HIF-1 α actually act against HSP90.

A series of such analogues were recently tested for their cytotoxic effect in TMZ-resistant GBM cells and two lead molecules with anticancer properties irrespective of MGMT and DNA mismatch repair pathway status were identified [69].

Tests to assess the cytotoxic and genotoxic effects in peripheral lymphocytes of healthy humans have been extensively used for safety evaluation of natural and synthetic compounds present in high concentrations in foods and in the environment as contaminants or for the evaluation of new specific molecules with anticancer potential [ 27, 34].

It has previously been established that several electrophilic molecules with anticancer properties, such as cisplatin and some other chemotherapeutic drugs with alkylating activity, as well as natural products like curcumin and flavonoids, can inhibit TrxR1 by blocking its Sec-containing catalytic center.

These preliminary results demonstrate that derivatives of this family can be attractive to develop new molecules with potent anticancer activity.

Evaluations of these molecules over 60 cell line panel of human cancer cells have identified two molecules with significant anticancer activities.

Many commercial small molecule drugs with anticancer, anti-inflammatory, and antimicrobial activity have been successfully associated with dendrimers such as poly amidoamine) (PAMAM), poly(propylene imine) (PPI or DAB) and poly etherhydroxylamine) (PEHAM) dendrimers, either via physical interactions or through chemical bonding ('prodrug approach').

It is of interest to design future experiments to identify pure polyphenol/flavonoid molecules in SBCG with anticancer activities.

The results from this study provide further evidence that analogs of the sesquiterpene MMB can be designed to afford molecules with significantly improved anticancer activity.