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Site-directed mutagenesis of eight cysteines was used to disrupt disulfide bonds to generate molecules with altered IgE-binding capacity.
Techniques to accelerate DTM calculations by assessing the contribution of grazing gas molecule collisions (gas molecules with altered trajectories by the potential interaction) without tracking grazing trajectories are further discussed.
Identifying the binding sites for drug molecules on HSA can aid in determining the structure activity relationship of albumin binding and assist in the design of molecules with altered albumin binding.
Each factor integrates signals from several upstream molecules with altered expression.
Insulin analogues are structurally modified molecules with altered pharmaco-kinetic and -dynamic properties compared to regular human insulin used by diabetic patients.
Several molecules with altered patterns of expression in obesity are involved in breast cancer (i.e., insulin and IGF-1, and adipokines) [ 16].
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Additionally, it was discovered that one commonly used GIVA cPLA2/GVIA inhibitoribitor, methyl arachidonyl fluorophosphonate (MAFP) from one commercial source, was found to inhibit GIIA sPLA2 and GV sPLA2, but not GIVA cPLA2, presumably due to oxidation of the compound during shipment, resulting in a different molecule with altered specificity.
The C-terminal carbohydrate-recognition domain (CRD) of DC-SIGN is preceded by a neck domain composed of eight 23-residue repeats which mediate molecule multimerization, and whose polymorphism correlates with altered susceptibility to SARS and HIV infection.
The KIR2DL3/2DP1 hybrid, in effect, encodes a KIR2DL3-like molecule with an altered cytoplasmic tail.
With altered destinations".
Understanding the basic pathophysiological mechanisms of cognitive decline and how the subcellular organization of signaling molecules is altered with cognitive decline could potentially yield novel therapeutic targets for neuronal aging and neurodegeneration.
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pathways with altered
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molecules with complex
molecules with different
molecules with complicated
molecules with overlapping
molecules with hERG
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molecules with identical
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molecules with structural
molecules with other
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