Sentence examples for molecules which failed from inspiring English sources

We also excluded all molecules, which failed with the descriptor calculation programs.

Not unexpectedly, there is no clear correlation between the percent of molecules which fail the Lipinski/Veber filters and those which are predicted to be BBB impermeable.

Such predicable pharmacokinetics properties are in opposition to the situation of less predictable synthetic molecules, which fail at an alarmingly high rate (90%) during clinical trials.

Using histological and molecular approaches, the authors demonstrate that the primary deficit is the abnormal accumulation of collagen molecules, which fail to be exported from the ER of chondrocytes and notochord cells.

Although in humans there were studies demonstrating increased serum resistin levels in individuals with obesity and/or type 2 diabetes [ 8– 10], resistin's biological role as an insulin resistance molecule was debated by others, which failed to confirm a causal relationship of circulating resistin with insulin sensitivity or other metabolic parameters [ 11, 12].

U.C. voted against the resolution, which failed.

group, which failed to achieve complete rejection.

Which fails to open.

This leads to the production of many different types of co-stimulatory molecules, which ensures that if one fails to boost the activation of CD8+ T cells, another molecule can do so instead.

The molecules which lack desired ADME profile will fail to elicit pharmacological activity in vivo.

Molecules which show significant activity in vitro often fail to produce meaningful activity in in vivo conditions due to rapid metabolism and resveratrol is one such molecule.