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The outlying molecules were filtered using p = 0.01.
This model was used as a query to identify molecules, with potential affinity for the target, and subsequently, these molecules were filtered using molecular docking.
Sequences matching tRNA, rRNA, DNA repeats and adaptor molecules were filtered out.
Molecules were filtered for a rank difference of at least 5000 between the active and inactive screen.
For each target, duplicate molecules were filtered from these three sets, so that in each only unique drug molecules were analysed (Fig. 1).
For sterilization, all Gd III -labeled molecules were filtered with 0.2 μm sterile filters prior to concentration determination and storaGd III -labeled
Similar(52)
5 8 In virtual screening large databases of drug-like molecules are filtered in a knowledge-driven approach to prioritize compounds for biological testing.
Fluorescence emission from individual Dendra2 molecules was filtered with a single band emission filter centered at 617 nm and a bandpass of 73 nm and recorded on an EMCCD camera (iXon 897 Andor Technology, Belfast, Ireland).
All exogenous signaling molecules and inhibitors were filtered using 0.22 μm diameter microporous membranes before use.
Moreover, molecules containing toxic groups were filtered using the 204 substructures for "warhead" chelators, frequent hitters, promiscuous inhibitors and other undesirable functional groups available in FAF-Drugs2 tool [71].
Further, the hepatotoxicity level of all the molecules were calculated, the molecules with liver toxic nature were filtered out.
More suggestions(15)
pathways were filtered
models were filtered
species were filtered
elements were filtered
molecules were designed
molecules were compared
molecules were considered
molecules were collected
molecules were synthesized
molecules were chosen
molecules were selected
molecules were expressed
molecules were shown
molecules were involved
molecules were constrained
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