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Exact(5)
To facilitate evaluation of nano-spatial distribution and organization of CD3, CD4 or CD8, nanostructures of these molecules were defined based on the nano-concept and immune-fluorescence dot sizes of them: (i) nanoclusters, ≤200 nm, (ii) nano-domains, >200 but <500 nm, and (iii) micro-domains, ≥500, as we recently described [24].
Immobile molecules were defined as being restricted to a radius of confinement equal to one pixel (rconf < 0.166 μm).
The compounds structures have been prepared (charge states of molecules were defined and hydrogens were added) by the Open Babel [ 46] and MARVIN programs.
Confined molecules were defined as non-immobile tracks with a diffusion coefficient D of less than 0.2 µm/s, and the remaining tracks were considered freely diffusive.
To facilitate evaluation of nanoscale distribution and organization of TCR/CD3 and GM1, nanostructures of these molecules were defined based on the nano-concept and immunofluorescence sizes of them: (i) ≤200 nm nanoclusters, (ii) >200 but <500 nm nanodomains, and (iii) ≥500 nm microdomains.
Similar(55)
The similarity of two molecules is defined as the difference of the number of atoms.
Cadherins and cadherin-related molecules are defined by having an ectodomain in which at least two consecutive calcium-binding cadherin repeats are present.
The similarity between two molecules is defined by any similarity coefficient (e.g. Tanimoto) available in SA2 applied to the selected fingerprint.
The ST [37 40] similarity measure, which quantifies the shape similarity between molecules, is defined as the following equation: ST = V AB V AA + V BB − V AB (5).
The prominent characteristics of the active molecules are defined, and the competition between cytochrome c, 4,4′-bipyridine, 1,2-bis(4-puridyl)ethylene and aldrithiol-4 for the adsorption at the gold electrode has been studied in particular.
In a PDB file, these molecules are defined within the HETATM record along with small molecule ligands, but for the purpose of our study they were not classified as drug-like.
More suggestions(15)
compounds were defined
pathways were defined
perpetrators were defined
species were defined
genes were defined
models were defined
elements were defined
molecules were compared
molecules were considered
molecules were produced
molecules were chosen
molecules was defined
molecules were shown
molecules were retained
molecules were involved
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