Sentence examples for molecules we demonstrate from inspiring English sources

Using two representative β-lactam molecules, we demonstrate that interaction with the channel correlates with facilitated translocation through the porin and thus enhances the transport efficiency.

Using a cocktail of cytokines and small molecules, we demonstrate that primitive neural stem (NS) cells derived from mouse ES cells and rat embryos can be maintained.

Among NTHI-induced SLF-derived molecules, we demonstrated that MCP-1/CCL2 is a major attractant enhancing migration and invasion of monocytes.

Using this molecule, we demonstrate that activation of FGFR1/KLB complex in mice leads to sustained stimulation of thermogenic activity in BAT and induction of WAT browning, resulting in the efficacious amelioration of obesity, insulin resistance and associated metabolic defects.

Using specific antibodies that recognize extracellular C-terminus of the ALCAM molecule we demonstrated that GD2-positive cell line (EL-4) and two GD2-negative cell lines (Jurkat and L1210) expressed ALCAM on their surface.

To refine our initially found results, we would retest them with a higher resolution of competitor molecules because we demonstrate in the validation experiments that the coefficients of variability are lower when the molecule numbers of target and competitor sequences in the samples are similar.

Therefore, interacting contiguous alpha-synuclein molecules, which we demonstrate are not only present in human brain tissues but strongly associated with disease, would be a necessary although by no means a sufficient step for disease propagation according to this hypothesis.

In addition to demonstrating a "catch-and-pass" reaction mechanism in a small molecule kinase, we demonstrate that binding of our analogs to the substrate capture site inhibits PPIP5K2.

Using a powerful combination of small-angle X-ray scattering and single-molecule imaging, we demonstrate that pro-MMP-9 possesses an elongated structure with two terminal globular domains connected by an unstructured OG domain.

In the present paper, we show that CX3CL1, which is endowed with only one TM domain, has a lateral diffusion that is slower than that of the CX3CR1, which, similarly to all GPCRs, is a 7-TM molecule, and we demonstrate that this slow diffusivity is due to the glycosylation of the mucin stalk and the aggregation generated by the TM domain.

Combining simulations, chemical synthesis, and single-molecule fluorescence spectroscopy, we demonstrate force sensing in single molecules.