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BMP ligands act as retrograde signalling molecules to regulate presynaptic development, and regulation of BMP receptors by endocytosis may be an important component of this signalling pathway.
Synthetic biology is now engineering riboswitches, ribozymes, small RNAs [ 78, 79], and other possible regulatory molecules to regulate protein synthesis, suggesting that sophisticated dynamic regulation of protein synthesis may be possible in the future.
RNA interference (RNAi) uses small RNA molecules to regulate transcriptional and post-transcriptional gene expression.
Growth factors play a critical role as signaling molecules to regulate cell behavior during embryonic development and postnatal tissue regeneration.
To offer an ideal hospitable environment for corneal keratocyte growth, the carrier materials can be functionalized with incorporation of signaling molecules to regulate cell biological events.
The ability of these molecules to regulate T-cell expansion and effector function and the dynamic integration of the co-stimulatory and T-cell receptor signals are just beginning to be explored.
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To our knowledge EGCG is the first natural small molecule to regulate RIG-I dependent signal transduction.
It serves as a transcription factor to regulate osteoclast-associated gene transcription and as a signaling molecule to regulate the RANK/RANKL signaling pathway.
However, the expression of this unusual cellular mechanism in key neurons organizing different aspects of feeding behavior, localized in different ganglia, suggests that it may function to allow a circulating molecule to regulate NO production, and thereby regulate different aspects of feeding behavior.
The rhythmic expression of PK2 in the SCN and the complementary distribution of PKR2 in most primary SCN target areas [20] [21] are consistent with the prospective role of PK2 as an output molecule to regulate multiple circadian rhythms in the rodent [15] [16].
We investigated whether the oxygen, determined by mitochondrial respiration, is the critical molecule to regulate localization (prenylation) via HMGR.
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CEO of Professional Science Editing for Scientists @ prosciediting.com