Sentence examples for molecules to cell from inspiring English sources

In the context of antibody drug conjugates (ADCs), noncleavable linkers provide a means to deliver cytotoxic small molecules to cell targets while reducing systemic toxicity caused by nontargeted release of the free drug.

As a consequence of infection, LC3, LAMP1 and MHC class II molecules are retained within the H. pylori-containing vacuoles and export of MHC class II molecules to cell surface is blocked.

These observations have revealed sequential signaling cascades, from input signaling molecules to cell fate decisions, acting via oscillating molecules.

I shall specifically analyze how aptamers [ 19, 20] (i) can be designed using various techniques, (ii) can be used as drugs to target certain structural sites that are responsible for various diseases, and (iii) can be used as drug carriers to carry other drug molecules to cell based target structural sites.

Electron tomography is providing a wealth of 3D structural data on biological components ranging from molecules to cells.

Owing to their high surface area and good biocompatibility, GQDs have the potential to be vectors for delivery protein or drug molecules to cells [6, 12, 17 19].

A double bead microsphere device that functions as a 3D scaffold and also delivers bioactive molecules to cells has been developed.

CXCL12, the natural ligand for CXCR4, and the small-molecule CXCR4 antagonist, AMD3100, bound the proteoliposomes with affinities close to those associated with the binding of these molecules to cells expressing CXCR4 and CD4.

Here, we report that cells exposed to cell surface SE-positive HLA-DR (human leukocyte antigen-DR) molecules, to cell-free recombinant proteins genetically engineered to express the SE motif, or to SE-positive synthetic peptide showed diminished cAMP-dependent signaling, increased ROS levels, and higher vulnerability to oxidative DNA damage.

Electroporation represents a platform technology for delivery of different molecules to cells and tissues.

Transfection relies on the introduction of miRNA molecules to cells containing the reagent.