Sentence examples for molecules to activate from inspiring English sources

Like TNFRs, TIR-containing receptors do not have catalytic activity and use intracellular adaptors and signal-transducing molecules to activate effector pathways [ 45].

The immunoproteasome (i-proteasome) enhances antigen presentation for MHC class I molecules to activate CD8+T lymphocyte.

Here we identify an essential role of α-SNAP in mediating functional coupling of Stim1 and Orai1 molecules to activate SOCE.

In this regard, substantial efforts to enhance the efficacy and safety of cell therapy are continuously growing along several fronts, including modifications to improve the reprogramming efficiency of inducible pluripotent stem cells (iPS), genetic engineering of adult stem cells, and administration of growth factors or small molecules to activate regenerative pathways in the injured heart.

"These findings showed that mammals and fruit flies use similar molecules to activate innate immunity when encountering pathogenic microorganisms," a press release by the Nobel foundation says.

When a high population density is achieved at a focus of infection, a positive feedback loop is initiated in which AhyR activates the ahyI gene, thus making more AHL signaling molecules to activate AhyR.

(2) How many RIG-I molecules are necessary per RNA molecule to activate both ATPase activity and an IFN response?

The tracer is delivered to patients in an inactive state, and the acidic environment surrounding apoptotic cells causes the molecule to activate.

These findings raised the possibility that externalized PS generated by axon severing is recognized by INA-1 indirectly via a linker molecule to activate the INA-1 CED-10 pathway.

Recent work demonstrated that eATP acts as a signal molecule to activate host inflammatory and immune response [2], [3], [4].

For example, two MT1-MMP molecules act with one TIMP-2 molecule to activate a pro-Gelatinase-A (Gel-A) molecule [18].