Sentence examples for molecules the cleavage from inspiring English sources

In addition, for many molecules, the cleavage fragments have important functions.

To remove the contaminating ZZ ligand and uncleaved ZZ-IGF-1 from the IGF-1 molecules, the cleavage mixture was passed over a small (3.0 ml) IgG-sepharose column previously washed with 10× vol of TST, 2× vol of TS and 2× vol of 5 mM ammonium acetate, pH 4.5.

Concurrently monitoring the release of noncovalently sequestered guest molecules and the cleavage of the hydrophobic moiety suggested that there is a clear correlation between covalent bond cleavage and guest molecule release.

During division a cell rounds up, disassembles the cytoskeleton and redistributes cytoskeletal proteins and other molecules into the cleavage furrow that forms by assembly and contraction of an actomyosin ring to partition the cytoplasm [ 34, 35].

The catalytic (cis) Gln residues of Ran (Gln69), Ras (Gln61) and Rho (Gln63) in the cognate GAP complexes overlay well and are in position to stabilise (and/or polarise) the water molecule for the cleavage step.

Ribozymes (Rz), RNA molecules that catalyze the cleavage of RNA substrates, are an interesting alternative to the RNAi approach to gene inactivation.

The same enzymes that facilitate the initial maturation of SUMO molecules also catalyze the cleavage from their substrates.

mRNA molecules for which the cleavage was successful yield two products (5' fragment or 3' fragment), which usually sediment in lighter fractions of the gradient than the full-length as they contain less ribosomes.

Through this cyclic hybridization hydrolysis process, an OTA molecule can trigger the cleavage of a large quantity of signal probes.

For instance, it may be tempting to analyze sE-cad levels in parallel with those of other key molecules or markers and to characterize sE-cad associated with CDH1 mutations at gene level both in vivo and in vitro or to expand knowledge about the candidate molecules triggering cleavage of the full length E-cad into its soluble form.

In eukaryotes a number of ncRNA-based molecules are directly involved in the cleavage and processing of other RNA molecules.