Sentence examples for molecules the activity from inspiring English sources

However, despite the abundance of antigen-presenting and costimulatory molecules, the activity of T cells derived from SF of RA patients activated by autologous (TSLP-primed) mDCs is strongly hampered.

Like other chemotactic molecules, the activity was decreased at higher ligand concentrations.

As differentiating keratinocytes progress through the depth of the epidermis and change their expression of signaling receptors and adhesion molecules, the activity of signaling pathways within the keratinocytes shifts, and settles to a new, local steady-state of activation.

Specifically, we examined the levels of Chl and related molecules, the activities of various enzymes, the expression of relevant genes, and changes in chloroplast ultrastructure.

These compounds often serve as lead molecules, the activities of which can be enhanced by chemical manipulation and by de novo synthesis [ 2, 3].

We validated our findings on an independent set of samples treated with molecules inducing the activity of different receptors and DC activation.

Some of these molecules promote the activity of others; some have the opposite effect; and together these molecules and their interactions form 'signaling networks'.

These molecules boost the activity of several enzymes, including one called JNK1.

This inhibition was not restricted only to the neutralization of the viral molecules, but the activity was extend to the suppression of the intracellular viral replication.

p21Waf1/Cip1 is one of the p53 target molecules, inhibiting the activity of the cyclinB1/Cdc2 complex [ 53], leading to a cell cycle arrest.

Molecules blocking the activity of this family of enzymes, collectively known as PDE inhibitors, have been a major focus of drug development, particularly for cardiovascular disease.