Sentence examples for molecules that simultaneously from inspiring English sources
Recent understanding of the systems that mediate complex disease states, has generated a search for molecules that simultaneously modulate more than one component of a pathologic pathway.
Significant progress has been made in identifying small molecules that simultaneously bind both the active site and a unique adjacent site that enables specific inhibition of individual PTP isoenzymes.
PROTAC molecules are bifunctional small molecules that simultaneously bind a target protein and an E3-ubiquitin ligase, thus causing ubiquitination and degradation of the target protein by the proteasome.
This implies that a combination of small molecules that simultaneously block Y177 [36], the protein binding SH2 domain and the proline rich region could suppress BCR-ABL induced leukemia despite maintenance of kinase activity.
Therefore, identification of small molecules that simultaneously activate the ROS MAPK pro-apoptotic pathway and block ROS-induced anti-apoptotic pathways may improve BC chemotherapy.
Creating new molecules that simultaneously enhance tumor cell killing and permit diagnostic tracking is vital to overcoming the limitations rendering current therapeutic regimens for terminal cancers ineffective.
The physical act of eating becomes an incorporation point of bioactive molecules that are simultaneously material and social.
Amphiphilic: A term describing molecules or surfaces that simultaneously possess both hydrophilic and hydrophobic properties.
The number of molecules that can be simultaneously classified in the serial environment is constrained by the amount of memory available in the machine.
For instance, sequencing of bacterial genomes using Pacific Biosciences's (PacBio's) single molecule sequencing approach that simultaneously allows the detection of deoxyribonucleic acid (DNA) methylation patterns in bacterial genomes is now routinely performed in many laboratories (Flusberg et al. 2010; Gomez-Escribano et al. 2016; Koren et al. 2013).
Our analysis of disease-related changes which take place in sensory neurons during sensitization led to the design of a molecule that would simultaneously inhibit peripheral NMDA receptors and voltage sensitive sodium channels.
